Geometric and Functional Change of Both Ventricles after Atrial Ventricular Septal Defect Closure

Interestingly, previous studies shows that there are some regional differences regarding the extent and the time course of deformational changes. 2) The regional heterogeneity in RV wall thickness and curvature may explain some of the variance in RV regional deformation. In ASD patients, RV lateral longitudinal strain is higher and RV septal strain is similar (or slightly higher) compared with healthy controls. 2)4)5) The difference between the septal and lateral wall deformation can be explained with the fact that 2 dimensional speckle tracking could not distinguish between right sided and left sided component of the septum. However, there is no difference of strain rate in ASD patients compared with healthy controls and this finding has demonstrated in some studies, 3)6)7) that systolic strain rate is mainly related to the change in contractility, whereas systolic strain primarily determined by the stroke volume and more dependent on volume overload. After the closure, strain and strain rate of most segments excluding apical lateral segment decrease immediately. Transcatheter device closure, an attractive alternative to cardiac surgery, has been increasingly performed and offered as a primary therapy for the secundum ASD. Also it is good for evaluation the pure effect excluding cardiopulmonary bypass effect regarding to volume unloading after ASD closure. Lower apical strain values shows strong correlation with sys-tolic pulmonary arterial pressure and global RV systolic function indices. The prognostic value of changes in systolic strain over time was notable especially in patients with severe pulmonary arterial hypertension. An individual improvement > 5% in RV strain at follow-up was correlated with better pulmonary hemodynamics, improved clinical status, and less evidence of right heart failures, and it also predicted greater long-term survival that was incremental over clinical factors and choice The secundum type atrial septal defect (ASD) is a relatively common congenital heart defect. The long-standing left to right shunt causes right ventricular (RV) volume overload and pulmonary vascular changes resulting in later RV pressure overload. Also it causes and results in reduced left ventricular (LV) preload, leading to a decrease in cardiac output. Therefore , in patients with significant ASD shunts, the RV chamber distends and the septum deviates toward the LV, resulting in a compressed LV. Transcatheter or surgical closure of the defect causes reverse remodeling of the both ventricles. However, such adaptation may take long time and can be in completion in adult patients. Standard echocardiographic studies in ASD patients showed higher …